Several Nature Identical Bioactive Molecules have been identified that facilitate the cellular mechanisms that promote longevity. These elements work to maximize cellular efficiency, and maintenance, and promote longevity. Hundreds of publications indicate that the right nature identical molecules or coenzymes may indeed alter our biological clock and promote a healthier, more athletic life.
Inside each cell in your body a beautiful invisible purposeful dance occurs, a ballet of highly coordinated movements and interactions of genes, molecules, enzymes and coenzymes. As we age, we naturally see losses in certain enzymes and coenzymes. Without these enzymes and coenzymes, our beautiful cellular ballet becomes less synchronized and more disorganized, which leads to aging. Some of our life choices and environmental exposures also contribute to altering these cellular processes and contribute to aging.
As We Age
As we age, deficiencies in cellular functions and maintenance start to physically manifest themselves as wrinkles, stiffness, hair loss, degeneration, etc. These deficiencies in cellular maintenance occur because enzymatic and cellular reactions become dysfunctional with time.
This cellular dysfunction can be minimized by three things:
- Replacing in our cells what we lose with age and amplifying what we know to be beneficial
- Creating the least stress on our cellular system by maintaining the best cellular milieu or environment
- A daily dose of 5 natural bioactive elements or coenzymes
Aging
Aging essentially occurs when cellular identity or specialization deteriorates and cellular growth arrests. We will focus on certain metabolic cellular failings that we can mitigate: foibles in the genome or the epigenome, shortcomings of cellular metabolism and flaws in extracellular mechanisms. All of these weak points lead to an erosion of cell maintenance, tissues, organs and subsequent aging. Recognize that, sadly, your biological age can surpass your chronological age depending on the life you live and your environmental choices. Our goal is the opposite - to slow down the processes that determine your biological age.
In order for this information to be compelling you will need to understand the cellular workings of the genome, the epigenome and certain cellular functions.
I don’t want to oversimplify these concepts, but I want to provide you with the basic science that will allow you to understand how certain cellular reactions can be nudged in our favor. Unfortunately, fine-tuning in biology requires us to look at the small things in the cell.
Protein Synthesis
Every cell in your body has the same DNA in its nucleus. What determines a brain cell from a skin cell is what proteins are made in that particular cell. These intracellular proteins give the cell its identity and allow the cell to maintain its specialization. The more perfect this process of protein synthesis, the slower you age. The more imperfect this process, the faster you age.
Some of the proteins that are made leave your cell and have extra-cellular functions such as making hyaluronic acid, collagen, and elastin to keep your skin plump and moist. Some of these proteins produce keratin to make your hair. Some of these proteins make hyaluronic acid and collagen that lubricate your joints. Hopefully, you can begin to see that if protein synthesis becomes dysfunctional you start to show all of the signs of aging, hair loss, stiff joints, skin wrinkles, etc.
Mitosis
Some cells in your body undergo a lot of mitosis such as skin cells and some cells undergo very little mitosis such as brain cells. Mitosis is part of the process of how we grow and how we maintain ourselves. The more perfect this process, the slower you age. The more imperfect this process, the faster you age. Each time a cell replicates the opportunity door for errors is opened which can lead to accelerated aging.
Autophagy
Is the process of recycling proteins that are misfolded inside the cell. These misfolded proteins need to be recycled or they accumulate in the cell and can essentially create “traffic and clutter” in the cell inhibiting normal cellular function. Unless these inactive proteins are recycled, aging is accelerated.
Epigenome
The genome is your complete set of genetic instructions, your complete set of DNA. Essentially, your genome is not the primary source of your aging. The epigenome is a multitude of chemical compounds that turn genes on and off by essentially spooling them around proteins or histones. This process of spooling and unspooling genes is how your cells turn genes on and off. This winding and unwinding of DNA is part of a highly coordinated ballet, an epigenetic dance, that your cells go through to remain healthy and specialized. If you want to maintain your cells, tissues and organs, this process has to occur in a specific fashion. Abnormalities with this epigenetic dance are what are believed to be the source of aging. When the epigenome falters, protein synthesis and mitosis falter.
Longevity Genes
There are specific genes that make specific proteins that are highly conserved throughout evolution and are amenable to manipulation. These genes, Sirtuins, AMPK and mTOR, are found in all forms of human life including unicellular organisms, plants, and humans and appear to be the most important longevity genes identified. Subsequent pamphlets will discuss in more detail how we can use molecular messengers to nudge these particular longevity genes in our favor to maintain the epigenome, protein synthesis, mitosis and autophagy.
Skin Wrinkles Occur as Part of Aging
Skin wrinkles illustrate how the small activities in the cell are not functioning as they should. Although skin wrinkles are easy to see, these same cellular deficiencies are occurring in all tissues of your body that you can’t see. They illustrate well the aging process and represent something that’s easy for the average person to see and understand. Cellular deficiencies slowly add up and lead to aging. Our goal is to enhance cellular mechanisms in a positive way and positively impact aging and all of its side effects.
So, You Say You Want to Stay Healthy
Well, what scientists and medical doctors are telling us today in the latest publications is that eating the right food and consuming the several identified nature identical bioactive molecules (NMN, Quercetin, Resveratrol, Berberine and Astragalus) is what can be done to maintain your tendons, ligaments, hair, skin, joints, heart, blood vessels, brain function, etc. Our goal is not just to slow your biological clock but also to keep you athletic and promote a healthier life.
Amplification
Natural Bioactive Nutrients
Four of these five Nature identical bioactive elements (Quercetin, Resveratrol, Astragalus and Berberine) can be obtained from plant-based diets but the amount you can ingest is very low. Nicotinamide mononucleotide (NMN) is a natural co-enzyme but it can’t be consumed in any appreciable amounts through the plant or meat-based diets.
- These natural bioactive elements need to be concentrated and ingested at higher concentrations in order to unlock the full capacity of their material benefits.
There are complementary cellular processes that occur to maintain longevity. The cellular processes that are necessary for cellular health require simultaneous and complementary cellular reactions to occur. Our recommendation is to encourage these complementary processes with the intake of all five of our recommended nature identical bioactive molecules in Nicotinamide mononucleotide (NMN), Quercetin, Resveratrol, Berberine (BBR) and Astragalus. When these nature identical bioactive elements are taken together, synergistic benefits have also been found.
Future Issues
Future issues will provide further information regarding Nicotinamide mononucleotide (NMN), Quercetin, Resveratrol, Astragalus and Berberine to help you make educated life choices. Nothing should be more important than extending our biological clock and promoting a healthier, more athletic life. We hope that this information will help you make an educated life choice and begin using Rebesana on a daily basis. This should be the one thing you do for yourself.
